Hated by Trolls, probably not, Hated by Darkness on the other hand.... (think of Vampires and their various vulnerabilities)
I think the important issue is that the "Loss" should be at least as great as the potential gain - a failure giving "hated by trolls" might be quite acceptable for a quest whose success gives you an equivalent "Trollfriend" rating - it is unlikely to be so for a quest which grants you the ability to transform yourself into a Shade at will...
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