Every human culture recognizes the five (or four or six or seven) elements and the eight (or six or ten or twelve) powers. Probably all the Elder Races do as well.
However, not all runes are actively worshiped by every culture. Some are seen as demonic or given propitiatary worship only. Frex, the Orlanthi do not worship Stasis, assigning it the status of a hostile entity (Yelm, Mostal, sometimes Zzabur). Many cultures only offer propitiatary worship to Death and Disorder (to keep them away), viewing them as terrible demons (like Humakt, Blaskarth, or Zorak Zoran).
Jeff
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