I think you answer your own point, pretty much (hence the longish quote): you can get people (though obviously not most of us listpotatoes) to run for 50 days on the trot (as it were), or to cite another example, bicycle round the whole of France at break-neck (or at least, break-clavicle) speeds for three weeks, but you couldn't get a horse to do that. So it depends on how 'long a run' it is you're interested in. It's also the basis for one documented 'how to catch a horse if you don't already have a horse' technique, incidentally... The fact that you're making it hard to the horse to feed presumably contributes to that. (Though it doesn't simply relate directly to bipeds vs quadruped or carnivores vs vegetarians, if one contrasts felinids and canids, for example, so I'm guessing it also relates to muscle geometry and perhaps especially, muscle chemistry too.)
Cheers,
Alex.
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